Trials / Unknown
UnknownNCT01856387
The Effect of neutrophil-to Lymphocyte Ratio in Preeclampsia- Eclampsia
the Predictive Value of neutrophil-to Lymphocyte Ratio on Preeclampsia- Eclampsia
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 600 (estimated)
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital · Academic / Other
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
Neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammation and endothelial dysfunction. In recent years, it has been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts,may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literature, many studies have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases ). However, little is known about the predictive values of NLR in pregnancy complications. This study aimed to evaluate the potential predictive value of NLR in preeclampsia- eclampsia.
Detailed description
In recent years, have been reported that the individual components of the differential white cell count, specifically the neutrophil and lymphocyte counts, may have clinical utility in predicting diseases. An elevated NLR has been shown to be a prognostic indicator in various malignancies. İn the literatüre have been shown that NLR have predictive value in determining the prognosis of various diseases (cardiac or noncardiac diseases.However, little is known about the predictive values of NLR and PLR in gestational DM, preeclampsia and the other pregnancy complications. Retrospective data were collected for patients who was diagnosed with , preeclampsia- eclampsia, The NLR was defined as the absolute neutrophil count divided by the absolute lymphocyte count.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | high neutrophil to lymphocyte ratio | |
| OTHER | normal neutrophil-to Lymphocyte ratio |
Timeline
- Start date
- 2013-05-01
- Primary completion
- 2014-04-01
- Completion
- 2014-05-01
- First posted
- 2013-05-17
- Last updated
- 2014-03-18
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT01856387. Inclusion in this directory is not an endorsement.