NCT01845753

Molecular Screening for Lynch Syndrome in Denmark

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (actual)
• Sponsor: Vejle Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A clinically applicably strategy for molecular screening for Lynch Syndrome is being implemented in Denmark. Based on sequential analysis with immunohistochemistry and methylation analysis, patients with possible hereditary colorectal cancer are identified. These patients are offered genetic risk assessment and counselling. The study hypothesis is that molecular screening will identify more patients with Lynch Syndrome than the family history alone. Prospective data collection is performed using established clinical databases.

Conditions

• Colorectal Cancer
• Lynch Syndrome
• HNPCC

Interventions

Type	Name	Description
OTHER	Observation	Observation

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-02-01
• Completion: 2019-12-31
• First posted: 2013-05-03
• Last updated: 2020-01-23

Locations

11 sites across 1 country: Denmark