NCT01843101

Investigation of Different Scanning Protocols for 3 Dimensional High-resolution Imaging of the Human Cornea With Optical Coherence Tomography (OCT) - A Pilot Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to develop a protocol for optimal corneal 3-dimensional imaging based on measurements in healthy volunteers. For this purpose, a customized ultra-high resolution Spectral Domain OCT will be used. To validate whether the protocol can also be applied in patients with corneal pathologies, for whom it is intended to be used, measurements in these patients will be performed. We propose to obtain images from patients with keratoconus, since this is one of the most frequent causes for corneal transplantations in Europe and from patients with corneal neovascularization which is a major cause of vision loss in several ophthalmic diseases. Based on the obtained measurement protocol, further studies investigating the pathophysiology or treatment success of several corneal pathologies can be planned.

Conditions

• Corneal Neovascularisation
• Keratoconus

Interventions

Type	Name	Description
DEVICE	Optical Coherence Tomography	Imaging of the cornea using ultrahigh resolution Spectral Domain OCT

Timeline

• Start date: 2014-03-14
• Primary completion: 2016-10-24
• Completion: 2016-10-24
• First posted: 2013-04-30
• Last updated: 2021-09-08

Locations

1 site across 1 country: Austria