NCT01840787

A Pilot Study on the Use of a Sensory Panel to Assess Comfort Between Three Different Contact Lenses

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 63 (actual)
• Sponsor: University of Waterloo · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Accepted

Summary

As new contact lens products continue to be developed and improved, it's becoming harder for some individuals to tell whether one product is different from another. In addition, not everyone has the same level of sensitivity of their eyes, making it difficult for these judgments to be made. The purpose of this study is to explore the idea of using a pre-determined "expert panel" of individuals who are able to tell differences between contact lenses based on their comfort.

Detailed description

As technology continues to advance, contact lenses and lens care products are becoming harder to differentiate. In addition, assessing comfort in clinical trials is complicated, with full-masking behind hard to achieve and the psychology of the participant having unknown impact on the results. While the development of a reliable system to assess comfort would be beneficial for the research and development of new products, the use of a "sensory panel" itself may also lead to a better understanding of the drivers of discomfort at the end of the day. The objective of the study is to explore the use of a sensory panel, defined as individuals who have a good correlation between subjective and objective measures of discomfort, at rating the comfort of various contact lenses. The hypothesis is that in the "discriminative" group, the matrix of paired comparisons (between lens dissimilarity) is related to the ranked comfort of the lenses, while for the "poorly discriminative" group, the matrix of the dissimilarities will be random. An additional hypothesis is that the "discriminative" group will be less random than the entire group.

Conditions

• Dry Eye Syndromes

Interventions

Type	Name	Description
DEVICE	balafilcon A (8.6)	To be worn for 8 hours in one eye, and its comfort compared to another lens on another eye.
DEVICE	balafilcon A (8.3)	To be worn for 8 hours in one eye, and its comfort compared to another lens on another eye.
DEVICE	senofilcon A	To be worn for 8 hours in one eye, and its comfort compared to another lens on another eye.

Timeline

• Start date: 2013-04-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2013-04-26
• Last updated: 2015-12-16

Locations

1 site across 1 country: Canada