NCT01836848

Non-invasive Measuring of Cerebral Perfusion After Severe Brain Injury With Near-infrared-spectroscopy and ICG

Continuous, Non-invasive Monitoring of Cerebral Oxygenation and Perfusion Using Near-infrared Spectroscopy With Indocyanine Green Perfusion Measurement in Patients With Traumatic Brain Injury, Intracerebral or Subarachnoid Hemorrhage

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Cologne · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to show if it is possible to detect secondary ischemic events in patients with severe brain injury or cerebral haemorrhage with the help of non-invasive near-infrared spectroscopy (NIRS) by using the indocyanine green measuring of cerebral perfusion.

Conditions

• Subarachnoid Hemorrhage, Aneurysmal
• Intracerebral Hemorrhage (ICH)
• Traumatic Brain Injury

Interventions

Type	Name	Description
PROCEDURE	measuring cerebral perfusion by NIRS with ICG	application of a bolus of 5mg indocyanine green (ICG) in 3ml saline 0,9% i.v. in 1 second and measuring the ICG turnover with the near-infrared-spectroscopy (NIRS)

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-12-01
• Completion: 2016-06-01
• First posted: 2013-04-22
• Last updated: 2013-04-22

Locations

1 site across 1 country: Germany