NCT01809977

Comparison of Partial Removal and Total Removal of the Corneal Epithelium on Keratoconus

Study of Surgical Methods for Keratoconus

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Isfahan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 16 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine which surgical method makes less corneal haze

Detailed description

Keratoconus is an asymmetric, bilateral, progressive non-inflammatory ectasia of the cornea. The investigators evaluate whether partial removal versus total removal of the corneal epithelium can lead to less corneal haze and better visual outcomes.

Conditions

• Keratoconus

Interventions

Type	Name	Description
PROCEDURE	collagen cross-linking procedure (total removal)	patients underwent Corneal collagen cross-linking procedure with totally corneal epithelium removing. Total removal was performed by mechanical debridement of the corneal epithelium over the central 9 mm.
PROCEDURE	collagen cross-linking procedure (partial removal)	patients underwent Corneal collagen cross-linking procedure with partially corneal epithelium removing. Partial removal was performed by removing a 3-mm width ring and leaving the central 3 mm of the cornea intact.

Timeline

• Start date: 2012-07-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2013-03-13
• Last updated: 2013-03-13

Locations

1 site across 1 country: Iran