NCT01797289

Prevalence of Pulmonary Embolism in Patients With Syncope

The Prevalence of Pulmonarym Embolism in Patients With the First Episode of Syncope

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 600 (actual)
• Sponsor: University of Padova · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

All patients consecutively referred with the first episode of transient and short-lasting loss of consciousness will have a diagnostic workup for the assessment of the most common causes of syncope, and will be evaluated for the presence of pulmonary embolism (PE) with the use of an internationally accepted algorithm including a pre-test clinical probability (PTP according to the method of Wells et al.) and a high-sensitivity quantitative D-dimer assay. If the PTP is low and D-dimer negative, PE will be excluded. All other patients will undergo confirmatory diagnostic tests (either computerized tomography or ventilation/perfusion lung scanning) in order to confirm or rule out the presence of PE.

Conditions

• Syncope
• Pulmonary Embolism

Interventions

Type	Name	Description
OTHER	Lung CT or V/Q scanning in patients with a high pre-test clinical probability of PE and/or a positive D-dimer

Timeline

• Start date: 2012-02-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2013-02-22
• Last updated: 2015-01-26

Locations

1 site across 1 country: Italy