Trials / Completed
CompletedNCT01796847
Relationship Between PTEN and Glycemic Variability and Outcome in Critically Ill Patients
Influence of PTEN on Glycemic Variability and Clinical Outcome in the Critically Ill Patient.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- University of Roma La Sapienza · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Glycemic variability in critically ill patients is a recognized negative prognostic factor. The molecular mechanisms determining inter-patients variability in glucose metabolism during stress are not fully understood. The Phosphatase and Tensin homolog (PTEN) is known to influence glucose homeostasis by interfering in intracellular insulin signaling. Aim of this study is to ascertain whether differential expression of PTEN in critically ill patients correlates with glycemic variability and clinical outcome.
Conditions
Timeline
- Start date
- 2012-12-01
- Primary completion
- 2014-12-01
- Completion
- 2015-05-01
- First posted
- 2013-02-22
- Last updated
- 2017-11-07
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT01796847. Inclusion in this directory is not an endorsement.