Clinical Trials Directory

Trials / Completed

CompletedNCT01796301

An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal Women

An Open-label, Randomized, Teriparatide-controlled Study to Evaluate the Effect of Treatment With Romosozumab in Postmenopausal Women With Osteoporosis Previously Treated With Bisphosphonate Therapy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
436 (actual)
Sponsor
Amgen · Industry
Sex
Female
Age
55 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study was to evaluate the effect of 12 months of treatment with romosozumab compared with teriparatide on total hip bone mineral density (BMD) in postmenopausal women with osteoporosis who were previously treated with bisphosphonate therapy.

Conditions

Interventions

TypeNameDescription
DRUGRomozosumabAdministered by subcutaneous injection once a month.
DRUGTeriparatideAdministered by subcutaneous injection once a day.

Timeline

Start date
2013-01-31
Primary completion
2015-05-14
Completion
2015-05-14
First posted
2013-02-21
Last updated
2022-11-29
Results posted
2018-11-08

Locations

50 sites across 11 countries: United States, Argentina, Belgium, Canada, Colombia, Czechia, Denmark, Hungary, Poland, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01796301. Inclusion in this directory is not an endorsement.