NCT01793922

POEM Trial: Multi-center Study Comparing Endoscopic Pneumodilation and Per Oral Endoscopic Myotomy (POEM)

A Prospective Randomized Multi-center Study Comparing Endoscopic Pneumodilation and Per Oral Endoscopic Myotomy (POEM) as Treatment of Idiopathic Achalasia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 132 (actual)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare the efficacy of per-oral endoscopic myotomy (POEM) to the efficacy of pneumodilation as the initial treatment of symptomatic idiopathic achalasia. It is hypothesized that POEM has a higher long-term efficacy than pneumodilation in treatment of therapy-naive patients with idiopathic achalasia.

Conditions

• Achalasia

Interventions

Type	Name	Description
PROCEDURE	PD	pneumodilation
PROCEDURE	POEM	peroral endoscopic myotomy

Timeline

• Start date: 2013-10-01
• Primary completion: 2021-06-21
• Completion: 2022-02-18
• First posted: 2013-02-18
• Last updated: 2026-03-23

Locations

1 site across 1 country: Belgium