NCT01781104

Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation

A Phase 2, Randomized, Double-blind, Placebo-controlled, Multiple Dose, Parallel Group Study to Evaluate the Efficacy, Safety, and Pharmacodynamics of RM-131 Administered to Patients With Chronic Constipation

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Motus Therapeutics, Inc. · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic transit, bowel consistency, bowel habits, abdominal pain, and other abdominal symptoms in patients with chronic constipation.

Conditions

• Constipation

Interventions

Type	Name	Description
DRUG	RM-131	Double blind RM-131 (100 ug) will be delivered subcutaneously once daily for 14 days.
DRUG	Placebo	Placebo delivered subcutaneously once daily for 14 days.

Timeline

• Start date: 2013-03-01
• Primary completion: 2014-09-01
• Completion: 2014-10-01
• First posted: 2013-01-31
• Last updated: 2016-09-23

Locations

3 sites across 1 country: United States