NCT01760070

Comparison of O-type Hybrid Knife and IT Knife in ESD

Comparison of O-type Hybrid Knife and IT Knife in Endoscopic Submucosal Dissection for Upper Gastrointestinal Neoplasms: a Prospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Xijing Hospital of Digestive Diseases · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

By combining injection and dissection capability together, O-type Hybrid knife could possibly shorten the endoscopic submucosal dissection procedure for upper gastrointestinal neoplasms.

Detailed description

Endoscopic submucosal dissection (ESD) has been accepted as an minimal invasive alternative to surgery for localized early upper gastrointestinal neoplasms recently. However, the procedure remains to be technically challenging and time consuming. Many modified methods or newly developed devices were developed to simplify the procedure. A new insulated tip dissecting knife (O-type Hybrid knife) has been recently developed with both injection and lateral cutting capability. The aim of this study was to investigate whether ESD procedure could be shortened with this new device.

Conditions

• Esophageal Cancer
• Esophageal Dysplasia
• Stomach Cancer
• Stomach Dysplasia

Interventions

Type	Name	Description
DEVICE	Hybrid knife	Use Hybrid knife in ESD procedure
DEVICE	IT knife	Use IT knife in ESD procedure.

Timeline

• Start date: 2012-12-01
• Primary completion: 2014-10-01
• Completion: 2014-12-01
• First posted: 2013-01-03
• Last updated: 2015-01-26

Locations

1 site across 1 country: China