Trials / Completed

CompletedNCT01757990

The Effect of Stevia Rebaudiana Extracts on Different Variables Related to Caries: an in Vitro and in Vivo Evaluation.

A Comparative Clinical Evaluation of the Effect of Stevia Rebaudiana Extracts and Sucrose on Dental Plaque pH (Stephan Curve Trend) Using a Microtouch Electrode in Healthy Volunteers. A Phase II Study.

Status: Completed
Phase: Phase 2
Study type: Interventional
Enrollment: 20 (actual)

Sponsor: Università degli Studi di Sassari · Academic / Other
Sex: All
Age: 20 Years – 55 Years
Healthy volunteers: Accepted

Summary

The aim of the present investigation was to evaluate the effect of stevioside and rebaudioside on several variables related to caries development. Two approaches were performed: an in vitro evaluation of the growth of a culture of mutans streptococci and in vivo randomized study on the effect of a single rinse containing stevioside and rebaudioside on plaque-pH.

Conditions

Dental Caries

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Effect of Stevioside and Rebaudioside on plaque pH	After measuring baseline plaque pH, the subjects rinsed for 1 minute with the sucrose solution. Plaque pH was then measured at 5, 10, 15, 30, 45 and 60 min after the mouth rinse.

Timeline

Start date: 2012-03-01
Primary completion: 2012-05-01
Completion: 2012-06-01
First posted: 2012-12-31
Last updated: 2013-01-15

Source: ClinicalTrials.gov record NCT01757990. Inclusion in this directory is not an endorsement.