NCT01748734

Cognitive Therapy in Reducing Depression in Patients With Cancer

An Examination of Cognitive Therapy for Depression in Cancer Patients.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to learn about treatment of depression in people who have any type of cancer. Cognitive therapy (CT) helps improve depressive symptoms by targeting patient's thoughts and behaviors. People who are depressed tend to have more negative or pessimistic thoughts. CT helps people evaluate the accuracy of their thoughts. By encouraging patients to develop more balanced views, symptoms of depression begin to improve

Detailed description

PRIMARY OBJECTIVES: I. Determine the efficacy of biobehavioral/cognitive therapy for cancer patients/survivors with major depression. II. Test for the covariation between reduction in depressive symptoms and improvements in quality of life. OUTLINE: Patients undergo cognitive behavioral therapy comprising progressive muscle relaxation training, behavioral activation, seeking information as a coping strategy, enhancing social support, cognitive reappraisal, assertive communication, changing depressive core beliefs, goal setting and planning for maintenance, and maintenance over 1 hour once weekly sessions for 12-20 weeks, biweekly sessions for 4-6 weeks, and monthly sessions for 2-3 months for a total of 16-26 sessions. After completion of study treatment, patients are followed up at 3, 6, and 12 months.

Conditions

• Depression

Interventions

Type	Name	Description
PROCEDURE	quality-of-life assessment	Ancillary studies
OTHER	questionnaire administration	Ancillary studies
OTHER	counseling intervention	Undergo cognitive behavioral therapy
BEHAVIORAL	behavioral intervention	Undergo cognitive behavioral therapy

Timeline

• Start date: 2011-03-01
• Primary completion: 2011-03-01
• First posted: 2012-12-12
• Last updated: 2015-06-04

Locations

1 site across 1 country: United States