NCT01747304

Evaluation of IVA (SE Femur Scans) to Identify Incomplete AFFs

Evaluation of Dual Energy X-ray Absorptiometry Scanners in the Identification of Atypical Femur Fractures - A Validation Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 285 (actual)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: Female
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

DXA scanners are routinely used to assess bone mineral density (BMD) and fracture risk in osteoporosis patients. They provide detailed bone imaging in a low radiation setting. Hologic manufactures scanners that are able to perform high definition instant vertebral fracture assessment (HD-IVA) used to screen at-risk patients for asymptomatic spine fractures instantly and reliably at the same time they are having their yearly BMD. We wish to investigate whether this same proven technology (HD-IVA scan mode) used on femurs (the scan mode is now called SE Femur scans) can be used to screen for atypical fractures of the femur in patients at risk for these debilitating fractures. In this proof of concept study, we propose to examine whether DXA scanners can provide a sensitive low radiation screening method to identify incomplete AFFs in patients with known incomplete AFFs and in patients at risk.

Conditions

• Atypical Femur Fracture

Interventions

Type	Name	Description
DEVICE	DXA Se femur scans (previously called IVA femur)	Single Energy Beam (previously called inter-vertebral assessment) by Dual energy x-ray absorptiometry of affected femur

Timeline

• Start date: 2012-07-01
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2012-12-11
• Last updated: 2025-08-19

Locations

1 site across 1 country: Canada