NCT01743443

Corneal Sensitivity Cross-linking Keratoconus

Corneal Sensitivity Changes Following Cross-linking for Progressive Lower Stage Keratoconus

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: Instituto de Olhos de Goiania · Academic / Other
• Sex: All
• Age: 18 Years – 26 Years
• Healthy volunteers: Not accepted

Summary

To evaluate corneal sensitivity changes following corneal cross-linking (CXL) in patients with progressive lower stage keratoconus.

Detailed description

Thirty eight eyes of 19 patients (11 women, 8 men) were included in a prospective, nonrandomized clinical study. Mean patient age was 22 years (range, 18-26 years). Inclusion criteria were low stage bilateral progressive keratoconus, transparent cornea and thinnest corneal thickness ≥ 440 µm. Using the Cochet-Bonnet esthesiometer central corneal sensitivity was measured preoperatively, after 7 days, and once a month after surgery until recovery of the baseline preoperative level. Normal levels of central corneal sensitivity were considered above 40mm.

Conditions

• Keratoconus

Interventions

Type	Name	Description
OTHER	Cochet-Bonnet esthesiometer central corneal sensitivity	Using the Cochet-Bonnet esthesiometer central corneal sensitivity was measured preoperatively, after 7 days, and once a month after surgery until recovery of the baseline preoperative level. Normal levels of central corneal sensitivity were considered above 40mm.

Timeline

• Start date: 2009-03-01
• Primary completion: 2012-10-01
• Completion: 2012-10-01
• First posted: 2012-12-06
• Last updated: 2012-12-06

Locations

1 site across 1 country: Brazil