Clinical Trials Directory

Trials / Completed

CompletedNCT01743001

Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome

A Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase 3 Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
226 (actual)
Sponsor
Actelion · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

Clinical study to assess the efficacy, safety, and tolerability of macitentan in subjects with Eisenmenger Syndrome.

Conditions

Interventions

TypeNameDescription
DRUGMacitentan 10 mgMacitentan 10 mg oral tablet once daily
DRUGPlaceboMacitentan-matching placebo oral tablet once daily

Timeline

Start date
2013-05-21
Primary completion
2016-12-01
Completion
2016-12-01
First posted
2012-12-06
Last updated
2018-02-23
Results posted
2018-01-30

Locations

55 sites across 21 countries: United States, Austria, Bulgaria, Chile, China, France, Germany, Greece, Israel, Malaysia, Mexico, Philippines, Poland, Portugal, Romania, Russia, Serbia, Spain, Turkey (Türkiye), United Kingdom, Vietnam

Source: ClinicalTrials.gov record NCT01743001. Inclusion in this directory is not an endorsement.