NCT01718912

Periodontal Disease Treatment of a Physically Challenged Population

The Effect of an Antibiotic-antifungal Rinse on Periodontal Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Oravital Inc · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush. These patients have considerable periodontal disease. There is a concern that these pathogens may have a detrimental effect on wound healing in other areas of the body. Hypothesis: Patients attending the dental department at TRI that are treated with the antibiotic-antifungal rinse containing metronidazole and nystatin will show substantial decrease in periodontal disease as measured by bleeding points and pocket depth when compared to the group that continues to use their regular oral hygiene methods (control group).

Conditions

• Periodontal Disease

Interventions

Type	Name	Description
DRUG	metronidazole-nystatin oral rinse

Timeline

• Start date: 2013-11-01
• Primary completion: 2014-09-01
• Completion: 2014-10-01
• First posted: 2012-10-31
• Last updated: 2016-03-31

Locations

1 site across 1 country: Canada