Trials / Completed
CompletedNCT01710800
Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor Therapy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 41 (actual)
- Sponsor
- Walter Reed National Military Medical Center · Federal
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine the effects of proton pump inhibitors (PPIs) on the total number of reflux episodes in the distal esophagus measured by impedance in patients with and without gastroesophageal reflux disease (GERD) based on 24-hour pH testing. In addition to changing the acidity of the refluxate, the investigators hypothesize that PPIs also reduce the total number of reflux episodes due to its anti-secretory effects.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esomeprazole | |
| DRUG | placebo |
Timeline
- Start date
- 2008-09-01
- Primary completion
- 2012-09-01
- Completion
- 2012-09-01
- First posted
- 2012-10-19
- Last updated
- 2013-01-09
- Results posted
- 2013-01-09
Source: ClinicalTrials.gov record NCT01710800. Inclusion in this directory is not an endorsement.