NCT01684124

An Assessment of the Feasibility and Safety of Conservative Oxygen Therapy in Critically Ill Patients

A Before-and-after Assessment of Conservative Oxygen Therapy vs. Standard Care in Critically Ill Mechanically Ventilated Patients

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: Austin Health · Other Government
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The investigators hypothesize that it is feasible and safe to deliver a conservative approach to oxygen therapy in mechanically ventilated critically ill patients (a tiem frame of, on average,10 days).

Detailed description

1. Identify patients likely to require ventilation until the day after tomorrow (a time frame of 36 hours of average) 2. Deliver a conservative oxygen therapy protocol while in ICU (a time frame on average of 10 days) 3. Target an oxygen saturation between 90 and 92% 4. Adjust FiO2 to achieve target SaO2 at all times 5. Assess percentage of time patient is within target 6. Assess for safety of this approach

Conditions

• Critical Illness

Interventions

Type	Name	Description
OTHER	conservative O2 therapy	target lower O2 saturation
OTHER	standard care

Timeline

• Start date: 2012-03-01
• Primary completion: 2013-03-01
• Completion: 2013-03-01
• First posted: 2012-09-12
• Last updated: 2013-07-11

Locations

1 site across 1 country: Australia