NCT01682993

Corneal Cross Linking and Topography Guided Excimer Laser Treatment

Topography Guided Excimer Laser Surface Ablation in Combination With Corneal Cross-linking (CCL) in Patients With Progressive Ectatic Corneal Disorders.

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Topography guided laser treatment enables the surgeon to correct higher order aberrations in corneas with irregular astigmatism. Several case reports and small uncontrolled trials have been published on the combination of this treatment with corneal cross linking (CCL) in patients with ectatic corneal diseases. This randomized study will evaluate the safety and efficacy of a combined treatment of corneal cross linking with a partial topography guided excimer laser treatment in eyes with progressive ectatic corneal diseases.

Conditions

• Keratoconus
• Pellucid Marginal Degeneration

Interventions

Type	Name	Description
OTHER	Topography guided Excimer Laser treatment and Corneal Cross Linking	A topography guided excimer laser treatment will be performed prior to CCL in one session.
OTHER	Corneal Cross Linking	A standard corneal cross linking procedure will be performed in this arm.

Timeline

• Start date: 2010-01-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2012-09-11
• Last updated: 2017-04-26

Locations

1 site across 1 country: Austria