Trials / Completed
CompletedNCT01639482
Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (actual)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 64 Years
- Healthy volunteers
- Not accepted
Summary
Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET).
Detailed description
Regional metabolic changes associated with response to 6 weeks of citalopram treatment, using 18-Fluorodeoxyglucose Positron Emission Tomography imaging, will be characterized (FDG PET). The following hypothesis will be tested: Antidepressant response or remission in depressed BPD patients will be associated with changes in cortical (prefrontal, parietal, premotor) and paralimbic (hippocampus, anterior cingulate, subgenual cingulate, posterior cingulate, and anterior insula) regions, consistent with SRI antidepressant response in unipolar depressed patients.
Conditions
Timeline
- Start date
- 2010-04-01
- Primary completion
- 2013-12-01
- Completion
- 2013-12-01
- First posted
- 2012-07-12
- Last updated
- 2019-03-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01639482. Inclusion in this directory is not an endorsement.