Clinical Trials Directory

Trials / No Longer Available

No Longer AvailableNCT01634230

Emergency Use of OCR-002 in Acute Liver Failure (ALF)

Emergency Use of OCR-002 (Ornithine Phenylacetate) in the Treatment of Patients With Acute Liver Failure

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Ocera Therapeutics, Inc. · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This study provides emergency use of the unapproved study medication in ALF patients with acute liver failure who are not responding to standard of care.

Detailed description

This is an open-label study in patients diagnosed with ALF who are not responding to the institution's standards of care. Standard of care may include, but is not limited to, administration of N-acetylcysteine, lactulose, hypothermia therapy, and consideration for orthotopic liver transplant.

Conditions

Interventions

TypeNameDescription
DRUGOCR-002daily dose: 10 g infused over 24 hours

Timeline

First posted
2012-07-06
Last updated
2021-06-24

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01634230. Inclusion in this directory is not an endorsement.