NCT01632215

Preoperative Gabapentine for Carpal Tunnel

Effect of Preoperative Gabapentine for Carpal Tunnel Syndrome

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to evaluate the postoperative analgesic effect of preoperative gabapentine for carpal tunnel syndrome surgery.

Detailed description

There was studied 40 patients. Group 1 patients received 600 mg of gabapentin 1 hour before surgery; G2 received placebo 1 hour before surgery. Anesthesia was regional intravenous block. Postoperative analgesia when needed was with acetaminophen. If needed was administered codeine. The evaluation of neuropathic pain was made by DN4 questionnaire. Pain intensity was assessed by numeric scale at block and after 30min, 1h, 2h, 2wk, 4wk, 6m. It was noted the duration of analgesia, and the amount of acetaminophen and codeine. The statistical program used for analysis of the results was the Instat Graph

Conditions

• Carpal Tunnel Syndrome

Interventions

Type	Name	Description
DRUG	Gabapentine	Gabapentine 600 mg 01 dose
OTHER	Sugar pill	Sugar pill 01 dose

Timeline

• Start date: 2010-03-01
• Primary completion: 2011-08-01
• Completion: 2012-03-01
• First posted: 2012-07-02
• Last updated: 2019-03-05
• Results posted: 2014-06-04