NCT01624337

Malaria Prevention Cambodia

A Randomized, Double Blind, Placebo-controlled Clinical Trial of Monthly DHA-piperaquine for Malaria Prevention in Cambodia.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 231 (estimated)
• Sponsor: Armed Forces Research Institute of Medical Sciences, Thailand · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Trial of monthly DHA-piperaquine for malaria prevention in health volunteers.

Detailed description

This is a two arm, randomized, double-blind, placebo controlled cohort study to determine the protective efficacy of a monthly 2 day treatment course of Dihydroartemisinin-Piperaquine (DP) in adult volunteers in malaria endemic areas of Cambodia.

Conditions

• Malaria

Interventions

Type	Name	Description
DRUG	DHA-piperaquine	Drug: Dihydroartemisinin piperaquine 40/320 mg tablets, 9 tablets total Arms: 2 day treatment course (4.5 tablets per day)
DRUG	placebo

Timeline

• Start date: 2012-05-01
• Primary completion: 2014-08-01
• Completion: 2015-06-01
• First posted: 2012-06-20
• Last updated: 2016-07-12

Locations

1 site across 1 country: Cambodia