NCT01585922

Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Beijing Hospital · Other Government
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

In order to identify the effect of noninvasive positive pressure ventilation (NPPV) on decreasing inflammatory response, improving the pathophysiological manifestation and reducing the morbidity and mortality in the moderate acute respiratory distress syndrome (ARDS) patients, the investigators conduct this clinical trial comparing NPPV with invasive mechanical ventilation in more than twenty ICUs in China.

Conditions

• Acute Respiratory Distress Syndrome

Interventions

Type	Name	Description
PROCEDURE	noninvasive positive pressure ventilation (NPPV)	Use NPPV to treat the ARDS patients,and we choose the NPPV ventilators in which the FiO2 can be fixed, for example: the BiPAP Vision or V60 of Phillip Respironics.
PROCEDURE	invasive mechanical ventilation	Intubate and give invasive mechanical ventilation to the other group patients when they are allocated at once.

Timeline

• Start date: 2012-07-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2012-04-26
• Last updated: 2018-11-21

Locations

1 site across 1 country: China