NCT01576263

Autologous Blood Transfusion After Local Infiltration

Autologous Blood Transfusion After Local Infiltration Analgesia With Ropivacaine in Total Knee and Hip Arthroplasty

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (actual)
• Sponsor: Northern Orthopaedic Division, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Total knee and hip arthroplasty for osteoarthritis is performed on still broader indications even in elderly patients with previous or current medical conditions. Especially comorbidity like cardiovascular diseases and conditions with increased risk of bleeding or previous thrombo-embolic events are major challenges. To facilitate safe use of ropivacaine as an analgesic, information on the concentrations levels after autologous blood transfusion following local infiltration analgesia is very crucial. However, very limited data are available. To verify the safety of autologous blood transfusion, ropivacaine concentrations were studied in 52 patients undergoing either total knee arthroplasty or total hip arthroplasty.

Conditions

• Total Hip Arthroplasty
• Total Knee Arthroplasty

Interventions

Type	Name	Description
DRUG	Autologous blood transfusion with ropivacaine	Local infiltration analgesia with ropivacaine 3 mg/kg, max 200 mg
DRUG	Autologous blood transfusion with ropivacaine	Local infiltration analgesia with ropivacaine 3 mg/kg, max 200 mg.

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-04-01
• Completion: 2010-06-01
• First posted: 2012-04-12
• Last updated: 2015-04-10

Locations

1 site across 1 country: Denmark