NCT01569217

Regional Distribution of Ventilation to Assess Respiratory Muscle Dysfunction

Construction of a Database to Identify Early Indicators of Respiratory Muscle Dysfunction in Neuromuscular Patients From the Optoelectronic Plethysmography Assessment of the Thoracoabdominal Motion

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Centre d'Investigation Clinique et Technologique 805 · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to better discriminate respiratory muscle dysfunction by comparing the measurements of thoracoabdominal motion obtained by an optoelectronic recording and the conventional tests of respiratory muscle strength. The final objective is to better select in the future the patients who need more specific assessment of diaphragmatic function like "maximal transdiaphragmatic pressure" measurement and "phrenic nerve stimulation".

Detailed description

All patients which had suspected respiratory muscle dysfunction will have usual exploration of the respiratory muscles according to the clinician prescription. These explorations can include : * Lung volumes in seating and supine position * Maximal inspiratory and expiratory pressures * Maximal sniff pressures And when diaphragmatic dysfunction is suspected : * Maximal transdiaphragmatic pressure * Phrenic nerve conduction These patients will also beneficiate to the determination of volume variations of the upper rib cage, the lower rib cage and the abdominal compartments by using Opto-electronic plethysmography.

Conditions

• Respiratory Failure
• Neuromuscular Disorder
• Diaphragmatic Paralysis

Timeline

• Start date: 2011-06-01
• Primary completion: 2018-06-01
• Completion: 2018-07-01
• First posted: 2012-04-03
• Last updated: 2017-05-01

Locations

1 site across 1 country: France