NCT01564745

Cough Determinants in Mechanically Ventilated Patients

Cough Determinants in Mechanically Ventilated Patients: a Physiological Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: University Hospital, Caen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In our knowledge there is only few data about the cough determinants in mechanically ventilated patients. However some failure of extubation is due to inefficiency cough. In order to determine some determinants of cough, the investigators propose to evaluate systematically different physiological parameters before and after extubation.

Detailed description

In order to evaluate, and identify the cough determinants, the investigators propose a physiological evaluation for each patients who were intubated and mechanically ventilated during at least 72 hours. Indeed inefficacy of cough after extubation is one of the main reason of extubation failure. However there is no any mean to evaluate it simply now.

Conditions

• Mechanical Ventilation

Interventions

Type	Name	Description
OTHER	Functional respiratory evaluation	Each enrolled patients has a pulmonary function test before and after extubation, and repeatedly at D1, D3, D5 (if they are always hospitalized)

Timeline

• Start date: 2012-03-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2012-03-28
• Last updated: 2019-04-22

Locations

2 sites across 1 country: France