NCT01561183

Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis

Vital Pulp Therapy for Management of Irreversible Pulpitis in Human Permanent Teeth: A Randomized Clinical Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 302 (actual)
• Sponsor: Shahid Beheshti University of Medical Sciences · Academic / Other
• Sex: All
• Age: 10 Years
• Healthy volunteers: Accepted

Summary

To compare the effect of different VPT methods using Calcium Enriched Mixture (CEM) cement for management of human dental pulp with irreversible pulpitis.

Detailed description

The purpose of this randomized clinical trial is to demonstrate the effect of four methods of Vital Pulp Therapy (VPT) using a new endodontic bio-material \[calcium enriched mixture (CEM) cement\] in pain relief as well as clinical/radiographic success, for management of irreversible pulpitis of human permanent teeth.

Conditions

• Irreversible Pulpitis

Interventions

Type	Name	Description
PROCEDURE	Indirect pulp capping (IPC)	Procedure: IPC The IPC will be performed as follow: * Anesthesia * isolation the tooth * access to the lesion * incomplete removal of carious tissue from the cavity walls * indirect pulp capping with ≈2 mm layer calcium enriched mixture cement * permanent filling with sandwich technique
PROCEDURE	Direct pulp capping (DPC)	Procedure: DPC The DPC will be performed as follow: * Anesthesia * isolation the tooth * access to the lesion * complete removal of carious tissue from the cavity walls result in pulp exposure * preparation of clot-free pulpal mound * direct pulp capping with ≈2 mm layer calcium enriched mixture cement * permanent filling with sandwich technique
PROCEDURE	Miniature pulpotomy (MP)	Procedure: MP The MP will be performed as follow: * Anesthesia * isolation the tooth * access to the lesion * complete removal of carious tissue from the cavity walls result in pulp exposure * intentionally removal of pulp horn (≈1 mm) * preparation of clot-free pulpal mound * direct pulp capping with ≈2 mm layer calcium enriched mixture cement * permanent filling with sandwich technique
PROCEDURE	Full pulpotomy (FP)	Procedure: FP The FP will be performed as follow: * Anesthesia * isolation the tooth * access to the lesion * complete removal of carious tissue from the cavity walls result in pulp exposure * pulpotomy * preparation of clot-free pulpal mound * direct pulp capping with ≈2 mm layer calcium enriched mixture cement * permanent filling with sandwich technique

Timeline

• Start date: 2012-03-01
• Primary completion: 2014-03-01
• Completion: 2016-12-01
• First posted: 2012-03-22
• Last updated: 2017-04-28

Locations

1 site across 1 country: Iran