Clinical Trials Directory

Trials / Completed

CompletedNCT01547533

Study of Benznidazole Transfer Into Breastmilk in Lactating Women With Chagas Disease

Study of Benznidazole Transfer Into Breastmilk in Lactating Women Treated for Chagas Disease

Status
Completed
Phase
Study type
Observational
Enrollment
10 (actual)
Sponsor
Hospital de Niños R. Gutierrez de Buenos Aires · Academic / Other
Sex
Female
Age
18 Years – 40 Years
Healthy volunteers
Not accepted

Summary

The investigators propose to study the transfer of benznidazole into breastmilk from the blood of lactating women who receive the drug for the treatment of Chagas disease. Breastmilk and blood samples will be obtained from these patients at given times after they take the clinically indicated medication, and the concentrations in both matrices will be compared to estimate degree of transfer, which in turn will be used to evaluate potential degree of exposure of infants breastfed by these women. This study will help clarify safety of continuing breastfeeding while receiving treatment with benznidazole for Chagas disease.

Conditions

Timeline

Start date
2011-08-01
Primary completion
2013-06-01
Completion
2013-12-01
First posted
2012-03-08
Last updated
2015-03-18

Locations

1 site across 1 country: Argentina

Source: ClinicalTrials.gov record NCT01547533. Inclusion in this directory is not an endorsement.