Trials / Withdrawn
WithdrawnNCT01543724
Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder
A Multimodal Brain Imaging Study to Investigate Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder: Glycogen Synthase Kinase 3β Single Nucleotide Polymorphisms and Gray Matter Volume Increase Following Lithium Treatment in Bipolar Disorder
- Status
- Withdrawn
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Ewha Womans University · Academic / Other
- Sex
- All
- Age
- 19 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The investigators will assess Li-induced gray matter volume changes with regard to the endophenotype of GSK3beta polymorphism. The changes of gray matter are supposed to be more attributable to neurotrophic and neuroprotective characteristics of Li, which were closely related to the inhibition of apoptotic activity of GSK3beta.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lithium | 10mg/kg/day for 12 weeks |
Timeline
- Start date
- 2015-06-01
- Primary completion
- 2017-12-31
- Completion
- 2017-12-31
- First posted
- 2012-03-05
- Last updated
- 2018-02-09
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01543724. Inclusion in this directory is not an endorsement.