NCT01534377

Interpersonal Psychotherapy for Adolescent Girls

Prevention of Depression in Maltreated and Nonmaltreated Adolescents

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 328 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: Female
• Age: 13 Years – 15 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate the efficacy of Interpersonal Psychotherapy for Adolescents (IPT-A) for the treatment of depression and prevention of depression in maltreated and nonmaltreated girls between the ages of 13-15 years old.

Detailed description

Child maltreatment poses a serious public health problem and heightens the risk of psychopathology across the life course. Adolescence also represents a peak time for the emergence of depressive disorders particularly in girls. Effective interventions to prevent and treat depression in low income adolescent girls with or without histories of maltreatment are needed. Three groups will be recruited: Maltreated Depressive Symptoms (MDS), Nonmaltreated Depressive Symptoms (NDS), and a Nonmaltreated Nonsymptomatic Comparison (NNC), comparable in SES, race/ethnicity, and household composition. The MDS and NDS groups will be randomized into IPT-A or Enhanced Care (EC). Adolescent girls in these groups will receive 13 sessions of therapy. Girls in the NNC group will only complete research visits. Research assessments will be conducted at T1 (baseline/prior to intervention), T2 (6-weeks mid-intervention), T3 (end of intervention), T4 (1-year post) and T5 (18 months post). Girls and their mothers will participate in these research sessions. A multi-level-of-analysis approach, integrating genotyping, hormone assays, cognitive testing, adolescent- and maternal-report, mother-teen observation, and DHS and school records will be utilized to assess the effectiveness of the interventions.

Conditions

• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Interpersonal Psychotherapy for Adolescents	Adolescents will receive IPT-A a manualized intervention for depression and prevention of depression that emphasizes current interpersonal relationships, focusing on their immediate social context.
BEHAVIORAL	Enhanced Care	Adolescents will receive enhanced care which is consistent with care typically provided in community settings to treat and prevent depression.

Timeline

• Start date: 2011-07-01
• Primary completion: 2018-06-01
• Completion: 2018-06-01
• First posted: 2012-02-16
• Last updated: 2018-08-03

Locations

1 site across 1 country: United States