NCT01521572

Effect of the Salbutamol on Mechanical Properties of Respiratory System

Effect of the Use of Salbutamol on the Mechanical Properties of the Respiratory System of Healthy Individuals, Smokers and COPD Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Rio de Janeiro State University · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to assess the bronchodilator response of salbutamol on respiratory mechanics of healthy individuals, smokers and COPD with varying degrees of airway obstruction.

Detailed description

Clinical evaluation will be conducted and anthropometric measurements, then the pulmonary function tests: forced oscillation technique (FOT), whole body plethysmography, spirometry and-administration of salbutamol aerosol for assessment of bronchodilator response. After 20 minutes, the individual will be evaluated again following the same sequence.

Conditions

• Smoking
• Airway Obstruction

Interventions

Type	Name	Description
DRUG	Salbutamol sulphate	bronchodilator test, beta2-agonist, short-acting, six hours duration, 400 micrograms.

Timeline

• Start date: 2011-06-01
• Primary completion: 2012-01-01
• Completion: 2012-09-01
• First posted: 2012-01-30
• Last updated: 2012-02-02

Locations

1 site across 1 country: Brazil