NCT01509482

Insulin Resistance in Idiopathic Oligospermia and Azoospermia

Insulin Resistance : a New Diagnosis of the Pathogenesis of Idiopathic Oligozoospermia and Non Obstructive Azoospermia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: The Egyptian IVF-ET Center · Academic / Other
• Sex: Male
• Age: 25 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Insulin resistance in men can be the underlying major factor in reproductive abnormalities ( chronic hypospermatogenesis ) as well as metabolic abnormalities similar to polycystic ovarian syndrome ( PCOS ) in women.

Detailed description

During the past decade IR has been recognized as a major contributor to the pathogenesis of chronic anovulation, hyperandrogenism and metabolic abnormalities associated with PCOS . Theoretically IR in men may result in a similar reproductive abnormalities ( chronic hypospermatogenesis ) as well as other metabolic abnormalities similar to what happens in PCOS in women .

Conditions

• Insulin Resistance
• Oligospermia
• Azoospermia

Interventions

Type	Name	Description
OTHER	blood samples	blood samples to test for primary and secondary outcome measures
OTHER	Blood samples	IR Cholesterol HDL LDL Fasting Glucose Triglycerides

Timeline

• Start date: 2012-01-01
• Primary completion: 2014-01-01
• Completion: 2014-04-01
• First posted: 2012-01-13
• Last updated: 2014-11-25

Locations

1 site across 1 country: Egypt