NCT01509430

DAHANCA 25B: Progressive Resistance Training as Intervention for Regaining Muscle Mass After Radiation Therapy in Patients With HNSCC

Progressive Resistance Training as Intervention for Regaining Muscle Mass After Radiation Therapy in Patients With HNSCC - a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Danish Head and Neck Cancer Group · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Head and neck cancer patients often experience a critical weight loss of around 10% following radiation therapy. Of this up to 70% is muscle mass and is an independent predictor of mortality, lowers muscle strength and functional performance. The purpose of this study is in a randomized controlled trial to investigate the effects of progressive resistance training (PRET) on changes in muscle mass, muscle strength and functional performance in head and neck cancer survivors. The investigators hypothesize that PRET has a positive effect on all primary endpoints and increases muscle mass, muscle strength and functional performance.

Conditions

• Head and Neck Cancer

Interventions

Type	Name	Description
OTHER	Progressive Resistance Exercise Training	12 weeks of Progressive Resistance Exercise Training followed by 12 weeks of self chosen training
OTHER	Progressive Resistance Exercise Training	12 weeks of self chosen training followed by 12 weeks of progressive resistance exercise training

Timeline

• Start date: 2011-10-01
• Primary completion: 2013-04-01
• Completion: 2013-04-01
• First posted: 2012-01-13
• Last updated: 2016-11-29

Locations

1 site across 1 country: Denmark