NCT01496950

Double-blind Randomized Clinical Trial of Transcranial Magnetic Stimulation in Chronic Migraine

Double-blind Randomized Clinical Trial to Evaluate Safety and Efficacy of Repetitive Transcranial Magnetic Stimulation in the Preventive Treatment of Chronic Migraine

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Hospital Israelita Albert Einstein · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether active repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex is safe and effective for preventive treatment of chronic migraine, compared to placebo repetitive transcranial magnetic stimulation.

Detailed description

Patients with chronic migraine according to the criteria of the International Headache Society will be randomized to either active repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex or placebo repetitive transcranial magnetic stimulation, in a total of 23 sessions of treatment (15 sessions in the first month and 8 sessions in the second month of treatment). Outcomes will be evaluated at baseline, after one, two months after treatment, and one month after end of treatment

Conditions

• Chronic Migraine

Interventions

Type	Name	Description
DEVICE	10Hz active rTMS	10Hz active rTMS delivered to the left dorsolateral prefrontal cortex
DEVICE	Placebo	10Hz placebo rTMS delivered to the vertex

Timeline

• Start date: 2008-10-01
• Primary completion: 2011-12-01
• Completion: 2012-02-01
• First posted: 2011-12-21
• Last updated: 2018-04-05

Locations

1 site across 1 country: Brazil