Trials / Completed
CompletedNCT01488071
A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous Medication
A Randomised, Double-blind, Parallel-group, Active-controlled, Flexible Dose Study Evaluating the Effects of [Vortioxetine] Lu AA21004 Versus Agomelatine in Adult Patients Suffering From Major Depressive Disorder With Inadequate Response to Antidepressant Treatment
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 495 (actual)
- Sponsor
- H. Lundbeck A/S · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The objective of the present study is to evaluate whether vortioxetine (10 or 20 mg/day) is at least as effective as agomelatine (25 to 50 mg/day) in patients with depressive symptoms that showed inadequate response to Serotonin Reuptake Inhibitors (SRI) antidepressants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Vortioxetine (Lu AA21004) | encapsulated tablets, daily, orally |
| DRUG | Agomelatine | encapsulated tablets, daily, orally |
Timeline
- Start date
- 2012-01-01
- Primary completion
- 2012-12-01
- First posted
- 2011-12-08
- Last updated
- 2014-03-26
- Results posted
- 2014-03-26
Source: ClinicalTrials.gov record NCT01488071. Inclusion in this directory is not an endorsement.