NCT01484145

Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail

An Unblinded Clinical Trial to Evaluate the Deposition of Terbinafine in the Nail Bed After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subungual Onychomycosis in the Great Toenail

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Nitric BioTherapeutics, Inc · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine how much terbinafine is delivered to the nail bed after treatment with a number of modifications to a previously studied method for iontophoretic delivery of terbinafine gel. Iontophoretic delivery involves the use of a small electric charge to deliver drug across skin and nails.

Conditions

• Onychomycosis

Interventions

Type	Name	Description
DRUG	Terbinafine HCl	4% w/w terbinafine HCL gel, single dose,

Timeline

• Start date: 2011-12-01
• Primary completion: 2012-03-01
• Completion: 2012-04-01
• First posted: 2011-12-02
• Last updated: 2012-10-19

Locations

1 site across 1 country: United States