| Not Yet Recruiting | Fractional CO₂ Laser or 40% Urea With Topical Fluconazole Microemulsion in Onychomycosis NCT07033962 | Assiut University | N/A |
| Recruiting | CLINICAL INVESTIGATION FOR THE EVALUATION OF EFFICACY AND SAFETY OF TWO PRODUCTS FOR THE TREATMENT OF ONYCHOMY NCT06689852 | Oystershell NV | N/A |
| Not Yet Recruiting | Evaluation of a Combination of Two Medical Devices and One Device Use in the Treatment of Toenail Onychomycosi NCT06175013 | Swiss Footcare Laboratories - Poderm Professional | N/A |
| Not Yet Recruiting | Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis NCT06485505 | Zagazig University | Phase 1 |
| Recruiting | A Study of ATB1651 in Adults With Mild to Moderate Onchomycosis NCT06327295 | AmtixBio Co., Ltd. | Phase 2 |
| Unknown | Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Trea NCT06254027 | Oystershell NV | N/A |
| Suspended | A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onyc NCT05491603 | DermBiont, Inc. | Phase 2 |
| Unknown | Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis NCT06074315 | Nail Genesis LLC | N/A |
| Unknown | Diode Laser and Photodynamic Therapy Vs. Ciclopirox. NCT05809297 | Universidad Complutense de Madrid | Phase 4 |
| Completed | Effectiveness and Safety of Nailner Brush 2in1 in Onychomycosis NCT05560841 | Karo Pharma AB | N/A |
| Active Not Recruiting | Mycosis Culture Collection From Dermatological Isolated NCT05482763 | University of Rome Tor Vergata | — |
| Unknown | Radiofrequency in Onychomycosis NCT05390190 | Cairo University | N/A |
| Unknown | Lasers in Onychomycosis NCT05415852 | Cairo University | N/A |
| Active Not Recruiting | A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO) NCT05279846 | Moberg Pharma AB | Phase 3 |
| Completed | A Study of ATB1651 in Adults With Mild to Moderate Onychomycosis NCT05089409 | AmtixBio Co., Ltd. | Phase 1 |
| Completed | Comparative Study Between Pulse Therapy With Oral Itraconazole Versus Continuous Oral Terbinafine Therapy for NCT05578950 | Combined Military Hospital Abbottabad | Phase 1 |
| Completed | An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection NCT05202366 | CAGE Bio Inc. | — |
| Completed | Human Factors Testing for OTC Use of the Erchonia® LunulaLaser NCT05626270 | Erchonia Corporation | N/A |
| Completed | Clinical Evaluation to Assess the Safety and Efficacy of GentleMax Pro Plus NCT04993066 | Candela Corporation | N/A |
| Completed | Alpha-bisabolol for Onychomycosis Treatment NCT04940520 | Universidade do Vale do Sapucai | Phase 1 |
| Completed | Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population NCT04327622 | LMC Diabetes & Endocrinology Ltd. | — |
| Completed | Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis NCT03814343 | Mahidol University | Phase 4 |
| Unknown | Laser Treatment for Onychomycosis in Diabetes NCT02019446 | BCDiabetes.Ca | N/A |
| Completed | A Study of the Systemic Absorption of MOB015B NCT03244280 | Moberg Pharma AB | Phase 1 |
| Completed | Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With NCT03216200 | DeviceFarm, Inc. | N/A |
| Completed | Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients NCT03168841 | Western University of Health Sciences | Phase 3 |
| Unknown | Study Efficacy and Safety in Comparative Use of Investigational Product Adjuvant Treatment in Onychomycosis NCT02961634 | MIP Brasil Indústria e Comércio de Produtos Farmacêuticos LTDA | Phase 3 |
| Unknown | The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosis NCT02644551 | 9305-9954 Quebec Inc | Phase 2 |
| Completed | Safety and Pharmacokinetics of Efinaconazole Topical Solution in Subjects With Mild to Severe Onychomycosis NCT02812771 | Bausch Health Americas, Inc. | Phase 4 |
| Completed | Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail NCT02798380 | Hallux, Inc. | Phase 2 |
| Completed | Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study NCT02933879 | Sun Pharmaceutical Industries, Inc. | Phase 2 |
| Unknown | Evaluating the Safety, Tolerability and Preliminary Efficacy of Plasma in Improving the Appearance of Onychomy NCT02724384 | Moe Medical Devices | N/A |
| Completed | An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Di NCT03405818 | Pfizer | Phase 4 |
| Completed | A Retrospective Analysis of the Effects of Low Level Laser Therapy on Toenail Onychomycosis NCT02588599 | Erchonia Corporation | N/A |
| Completed | Study Evaluating the Effect of Jublia on Dermatophytomas NCT03098615 | University of Alabama at Birmingham | Phase 4 |
| Completed | Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosi NCT02549001 | Polichem S.A. | Phase 3 |
| Completed | A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment NCT02464826 | Mahidol University | Phase 4 |
| Completed | Laser Therapy for Onychomycosis in Patients Wih Diabetes at Risk for Diabetic Foot Complications NCT01996995 | Medical Research Foundation, The Netherlands | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail NCT02267356 | Viamet | Phase 2 |
| Completed | Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great To NCT02355899 | photonamic GmbH & Co. KG | Phase 2 |
| Completed | Clinical Evaluation of the Efficacy of a Medical Device in Treatment of Toenail Onychomycosis NCT03289871 | Oystershell NV | N/A |
| Completed | Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail NCT02343627 | Sun Pharmaceutical Industries, Inc. | Phase 2 |
| Unknown | Evaluation of the Efficacy of CURE-EX Treatment in Onychomycosis NCT02436291 | MB Mazor Ltd. | Phase 4 |
| Completed | Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population NCT02547701 | Polichem S.A. | Phase 3 |
| Completed | Efficacy and Safety Study of ME1111 in Patients With Onychomycosis NCT02022215 | Meiji Seika Pharma Co., Ltd. | Phase 2 |
| Completed | Chart Review of the Efficacy of the GenesisPlus 1064 nm Nd:YAG Laser in the Treatment of Onychomycosis NCT02445495 | Jason K Rivers, MD, FRCPC, FAAD | — |
| Completed | Resin vs. Amorolfine vs. Terbinafine Treatment in Onychomycosis NCT01851590 | Helsinki University Central Hospital | Phase 4 |
| Completed | Pulsed Dye Laser Treatment of Onychomycosis NCT01915355 | Thomas Jefferson University | N/A |
| Completed | Pilot Study to Evaluate Plasma Treatment of Onychomycosis NCT01819051 | Moe Medical Devices | N/A |
| Completed | Pharmacokinetics and Safety Study of ME1111 in Moderate to Severe Onychomycosis Patients NCT01841996 | Meiji Seika Pharma Co., Ltd. | Phase 1 |
| Completed | Study of Erchonia Low Level Laser Light Therapy to Treat Toenail Fungus NCT02242019 | Erchonia Corporation | N/A |
| Unknown | Optimizing the Treatment of Toenail Onychomycosis Using a New Transdermal Patch Combined With Terbinafine/Keto NCT01615913 | Taiwan Biotech Co., Ltd. | Phase 1 |
| Completed | Evaluation of an Oligonucleotide Array for Rapid Identification of Dermatophytes in Clinical Specimens NCT02270697 | National Cheng-Kung University Hospital | — |
| Unknown | Erbium-doped Yttrium Aluminium Garnet Laser(Er:Yag)Associated With Amorolfine Lacquer in the Treatment of Onyc NCT01528813 | Brasilia University Hospital | Phase 2 |
| Completed | Deposition of Terbinafine After Iontophoretic Application of ETS Terbinafine Gel in Subjects With Distal Subun NCT01484145 | Nitric BioTherapeutics, Inc | Phase 2 |
| Completed | Diode Laser Treatment of Onychomycosis NCT01452490 | ConBio, a Cynosure Company | N/A |
| Completed | Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser NCT01666002 | Stanford University | N/A |
| Completed | Safety & Efficacy Study of HTU-520 in the Treatment of Distal Subungual Onychomycosis of the Toenail NCT01400594 | Hisamitsu Pharmaceutical Co., Inc. | Phase 2 |
| Completed | Study of the Use of Low Level Laser Light Therapy to Treat Toenail Fungus NCT01534689 | Erchonia Corporation | N/A |
| Completed | Efficacy and Safety of Two Treatment Regimens of Topical MOB015 in Adults With Distal Subungual Onychomycosis NCT01246518 | Moberg Pharma AB | Phase 2 |
| Completed | Open-Label Pharmacokinetics (PK)/Safety Study of Luliconazole Solution, 10% in Distal Subungual Onychomycosis NCT01044381 | Topica Pharmaceuticals | Phase 1 / Phase 2 |
| Completed | A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Def NCT01180491 | Moberg Pharma AB | N/A |
| Terminated | Safety & Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails NCT01208168 | Promius Pharma, LLC | Phase 3 |
| Terminated | Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails NCT01208129 | Promius Pharma, LLC | Phase 3 |
| Completed | Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosis NCT01080079 | Nitric BioTherapeutics, Inc | Phase 2 |
| Unknown | TDT 067 Onychomycosis Study NCT01145807 | Celtic Pharma Development Services | Phase 3 |
| Completed | TDT 067 Open Label Multi-Dose Onychomycosis Study NCT01790165 | Celtic Pharma Development Services | Phase 2 |
| Completed | A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 NCT01039883 | Stiefel, a GSK Company | Phase 1 |
| Completed | Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis NCT01008033 | Dow Pharmaceutical Sciences | Phase 3 |
| Completed | The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis NCT01007708 | Dow Pharmaceutical Sciences | Phase 3 |
| Withdrawn | Effectiveness of Podiatry Care on Onychomycosis (EPOCAON) NCT00938925 | University of Malaga | N/A |
| Completed | A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus NCT01014962 | Stiefel, a GSK Company | Phase 1 |
| Unknown | Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream NCT01014637 | Pierre Fabre Dermo Cosmetique | Phase 4 |
| Completed | Single-blind Evaluation of Device to Nail Micro-drilling in Onychomycosis NCT00941317 | Galderma R&D | Phase 1 |
| Completed | PinPointe FootLaser for the Treatment of Onychomycosis NCT00935649 | PathoLase, Inc. | Phase 2 / Phase 3 |
| Completed | Study Comparing SUBA™-Itraconazole With SPORANOX® (Itraconazole) in the Treatment of Onychomycosis NCT00791219 | Halcygen Pharmaceuticals Limited | Phase 2 |
| Unknown | Treating Onychomychosis NCT00776464 | Nomir Medical Technologies | Phase 2 / Phase 3 |
| Completed | Iontophoretic Application of Terbinafine Gel to the Large Toe Nail NCT00768768 | Transport Pharmaceuticals | Phase 1 |
| Unknown | Efficacy and Safety of RV4104A Ointment in Onychomycosis NCT00808366 | Pierre Fabre Dermo Cosmetique | N/A |
| Completed | Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste NCT00781820 | Bayer | Phase 3 |
| Completed | Anti-mold Azole in the Prophylaxis for Invasive Fusariosis NCT02714504 | Universidade Federal do Rio de Janeiro | N/A |
| Completed | Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomyco NCT00730405 | Stiefel, a GSK Company | Phase 2 |
| Completed | Efficacy Study of LIQUICURE™ to Treat Toe Nail Fungus NCT00960089 | Chesson Laboratory Associates, Inc | N/A |
| Unknown | Using Light Therapy to Treat Toe Nail Fungus NCT00771732 | Nomir Medical Technologies | Phase 2 |
| Completed | A Dose-Ranging Study Evaluating the Safety and Efficacy of IDP-108 in Patients With Onychomycosis NCT00777868 | Dow Pharmaceutical Sciences | Phase 2 |
| Completed | A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Trea NCT00491764 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME II) NCT00679601 | Pfizer | Phase 2 |
| Completed | Efficacy, Safety and Tolerability of Topical 10% Terbinafine Hydrogen Chloride Versus 5% Amorolfine Nail Lacqu NCT00459537 | Novartis | Phase 3 |
| Completed | Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail NCT01278394 | Pfizer | Phase 2 |
| Completed | Cumulative Irritation Test NCT00680095 | Pfizer | Phase 1 |
| Completed | Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail NCT00453271 | NanoBio Corporation | Phase 2 |
| Completed | Efficacy, Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of NCT00443898 | Novartis Pharmaceuticals | Phase 3 |
| Completed | Efficacy Safety, and Tolerability of Topical Terbinafine in Patients With Mild to Moderate Toenail Fungus of t NCT00443820 | Novartis Pharmaceuticals | Phase 3 |
| Completed | A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenail NCT00385502 | Abeona Therapeutics, Inc | Phase 2 |
| Completed | Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail. NCT00356915 | Stiefel, a GSK Company | Phase 3 |
| Completed | Safety and Efficacy Evaluation of Topically Applied AN2690 Solutions for Subjects With Onychomycosis NCT00680134 | Pfizer | Phase 2 |
| Completed | Absorption and Systemic Study of AN2690 in Patients With Moderate to Severe Onychomycosis (ADME I) NCT00680160 | Pfizer | Phase 2 |
| Completed | Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail NCT00679523 | Pfizer | Phase 2 |
| Completed | Topical Gel Anti-Fungal Agent for Tinea Unguium NCT00253305 | MediQuest Therapeutics | Phase 2 |
| Completed | Spread of Dermatophytes Among Families NCT00233493 | University Hospitals Cleveland Medical Center | — |
| Completed | Bioequivalency Study of Terbinafine Tablets Under Fasting Conditions NCT00602342 | Roxane Laboratories | N/A |
| Completed | Bioequivalency Study of Terbinafine Tablets Under Fed Conditions NCT00602251 | Roxane Laboratories | N/A |
| Completed | Topical Penlac Nail Lacquer for Onychomycosis in Children NCT01419847 | Rady Children's Hospital, San Diego | Phase 4 |