NCT01475084

Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare cryobiopsies with forceps biopsies during semirigid thoracoscopy.

Detailed description

The investigators are going to compare diagnostic yield and size, morphological features, immunohistochemistry as measures of the quality of the samples. The secondary aim is to evaluate safety with focus on bleeding intensity.

Conditions

• Pleural Effusion
• Pleural Diseases

Interventions

Type	Name	Description
DEVICE	cryobiopsy (Autoclavable cryoprobe 20416-032 (ERBE, Germany) Flexible FB-55CD-1 Olympus forceps	The tip of the cryoprobe will be attached to suspicious part of parietal pleura and activated by footswitch for 3 seconds. The frozen tissue is going to be extracted by gently pulling of the probe. The probe with the attached biopsy sample is going to be removed together with the thoracoscope through trocar. The biopsy sample will be released from the probe by thawing in the saline. Forceps biopsy will be performed on usual way.

Timeline

• Start date: 2011-11-01
• Primary completion: 2014-11-01
• Completion: 2014-11-01
• First posted: 2011-11-21
• Last updated: 2015-09-10

Locations

1 site across 1 country: Slovenia