NCT01447641

Sleep, Circadian Rhythms and Cluster Headache

Characterisation of Sleep and Circadian Physiology in Individuals With Cluster Headache

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: University of Surrey · Academic / Other
• Sex: All
• Age: 16 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess both the sleep and circadian (24-hourly biological rhythms) physiology of people with cluster headache. For sufferers with the episodic form of the disorder this will involve observation at two separate time points, once when experiencing attacks (in-bout) and once when attack free (out-of-bout). The study will include measurement of basic rest-activity patterns, sleep timing and timing of individual attacks, as well as a more detailed study recording sleep and circadian rhythms under clinical conditions over consecutive nights. Studying the differences in these processes in single individuals when they are both experiencing and free from attacks might provide insight into the brain mechanisms involved in triggering the bouts of attacks and individual attacks themselves. An improved understanding of this area may help design improved treatment options in future.

Conditions

• Cluster Headache

Interventions

Type	Name	Description
OTHER	Polysomnography	Overnight physiological recording of sleep
OTHER	Actigraphy	Wristwatch activity to measure basic rest activity cycle and sleep efficiency

Timeline

• Start date: 2011-08-01
• Primary completion: 2017-04-01
• Completion: 2017-04-01
• First posted: 2011-10-06
• Last updated: 2017-04-13

Locations

1 site across 1 country: United Kingdom