NCT01431443

Consumption of Chocolate in Pregnant Women.

Consumption of Chocolate in Pregnant Women at High Risk for Preeclampsia.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: Laval University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the acute and chronic effect of consumption of flavanol-rich chocolate on endothelium function in pregnant women at high risk for preeclampsia.

Detailed description

Although numerous strategies have been studied, no effective prevention or treatment of preeclampsia is yet available for pregnant women. This is surprising considering the growing body of literature that supports the hypothesis of a beneficial effect of dark chocolate consumption through the activity of flavanols on the endothelial function and blood pressure regulation, to find any clinical data among pregnant women with preeclampsia. The primary objective of the trial is to investigate the acute and chronic effect of consumption of flavanol-rich chocolate on endothelial function in pregnant women at high risk of preeclampsia. This 12-week efficacy study will permit us to verify the sustainability of the effect of daily intake of flavanol-rich chocolate intake.

Conditions

• Preeclampsia

Interventions

Type	Name	Description
OTHER	Flavanol-rich chocolate	The aim of this study is to evaluate the beneficial effect of dark chocolate consumption through the activity of flavanols on the endothelial function and blood pressure regulation, in acute (after 3 hours) and chronic effect (12 weeks), among pregnant women at high risk for preeclampsia.
OTHER	Placebo Chocolate	Placebo intervention

Timeline

• Start date: 2011-05-01
• Primary completion: 2014-09-01
• Completion: 2014-09-01
• First posted: 2011-09-09
• Last updated: 2015-04-09

Locations

1 site across 1 country: Canada