NCT01421082

Evaluation of Physiologic Parameters to Study the Mechanism of Action of the Lung Volume Reduction Coil in Subjects With Homogeneous Emphysema

Evaluation of Physiologic Parameters to Study the Mechanism of Action of the PneumRx, Inc. Lung Volume Reduction Coil (LVRC) in Subjects With Homogeneous Emphysema

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Boston Scientific Corporation · Industry
• Sex: All
• Age: 35 Years
• Healthy volunteers: Not accepted

Summary

The PneumRx Lung Volume Reduction Coil (LVRC) has been shown to effectively improve quality of life, exercise capacity, and static lung volumes, in patients with emphysema. The mechanism of action for these effects is believed to be related to the restoration of elastic recoil to lung parenchyma that has been damaged by emphysema. The objective of this study is to evaluate several physiologic parameters which should provide measures directly related to the mechanism of action by which the coils produce these outcomes.

Conditions

• Emphysema

Interventions

Type	Name	Description
DEVICE	Lung Volume Reduction Coil (LVRC) (PneumRx, Inc.)	Lung Volume Reduction Coil (LVRC)

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-03-01
• Completion: 2013-03-01
• First posted: 2011-08-22
• Last updated: 2021-07-16

Locations

1 site across 1 country: Netherlands