NCT01409304

Effectiveness of Deep Transcranial Magnetic Stimulation in Depression

Effectiveness of Deep Transcranial Magnetic Stimulation for Treating Major Depression: a Pilot Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Douglas Mental Health University Institute · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

We intend to investigate whether deep transcranial magnetic stimulation (DTMS), a novel brain stimulation technique, is effective for treating major depression. We hypothesize that 4 weeks of DTMS will be associated with significant improvements in depressive and anxious symptoms without significant side effects.

Detailed description

The aim of this pilot study is to assess, naturalistically, the effectiveness of deep transcranial magnetic stimulation (DTMS) in a sample of subjects with treatment-resistant depression. To do this, enrolled depressed outpatients will be assigned to receive 4 weeks of daily DTMS and will be evaluated at baseline and during week 5. We hypothesize that treatment with DTMS will be associated with significant clinical improvements in depressive and anxious symptoms, and will be well tolerated.

Conditions

• Major Depressive Disorder

Interventions

Type	Name	Description
DEVICE	Deep Transcranial Magnetic Stimulation (DTMS)	DTMS will be administered according to the following parameters: 18 Hz in 84 trains of 2 seconds duration, with 20 seconds inter-train interval (3,024 pulses per session) at 120% of the resting motor threshold.

Timeline

• Start date: 2011-10-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2011-08-04
• Last updated: 2013-01-18

Locations

1 site across 1 country: Canada