NCT01405846

Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to Gefitinib

Tyrosine Kinase Inhibitors in DyplAsia of Lung Epithelium

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Papworth Hospital NHS Foundation Trust · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

We are going to use a special type of bronchoscopy test to examine patients who have had previous surgical treatment for lung cancer or head and neck cancer. The aim is to determine a) whether we can identify precancerous changes in their airways b) whether this type of testing is acceptable and c) get an initial idea of whether a new drug called gefitinib has any effect on precancerous areas in the airway.

Conditions

• Lung Cancer
• Head and Neck Cancer

Interventions

Type	Name	Description
DRUG	Gefitinib	250mg od for 6 months

Timeline

• Start date: 2011-12-01
• Primary completion: 2016-04-01
• Completion: 2016-06-01
• First posted: 2011-07-29
• Last updated: 2016-08-19

Locations

1 site across 1 country: United Kingdom