NCT01383915

Clinical Risk State for Bipolar Disorder in Adolescents

Characterizing the Clinical Risk State for Bipolar Disorder in Adolescents

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 402 (estimated)
• Sponsor: Northwell Health · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: Accepted

Summary

Aim: The purpose of the study is to characterize the at-risk phases preceding a first episode of bipolar disorder and of schizophrenia, and to identify clinical and biological predictors of the disease development. Hypothesis a: Over 6-24 months, 25% of at-risk youth will develop the full manifestations of Bipolar Disorder (BPD) or schizophrenia. Hypothesis b: The symptoms utilized for characterizing the at-risk phase of BPD will differentiate between individuals developing BPD and schizophrenia.

Detailed description

Prospective, naturalistic, cohort study aiming to characterizing the bipolar and psychotic prodrome thoroughly with a variety of clinical and biological measures.

Conditions

• Bipolar Disorder
• Schizophrenia

Timeline

• Start date: 2009-09-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2011-06-28
• Last updated: 2023-04-04

Locations

1 site across 1 country: United States