NCT01376791

Assess the Effect of Treating Periodontal Disease on Cardiovascular Function in Young Adults

Oral Flora, Periodontitis, and Vascular Dysfunction in Young Native Americans.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 92 (actual)
• Sponsor: San Diego State University · Academic / Other
• Sex: All
• Age: 21 Years – 40 Years
• Healthy volunteers: Accepted

Summary

We propose to examine a population of Native Americans who have had little or no dental care, and to determine if periodontal disease is associated with early signs of vascular dysfunction or systemic inflammation. We then propose to treat the periodontitis and re-evaluate vascular function. We will determine if gingivitis or mild/moderate periodontitis is associated with detectable vascular dysfunction. Microbial metagenomics will be correlated with vascular function.

Conditions

• Periodontal Disease
• Atherosclerosis

Timeline

• Start date: 2010-12-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2011-06-20
• Last updated: 2013-04-23

Locations

1 site across 1 country: United States