NCT01374737

ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children

ED50 of Dexmedetomidine for Reduction of Emergence Agitation Incidence Undergoing Tonsillectomy or Adenoidectomy in Desflurane Anesthesia Following Sevoflurane Induction in Children

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in children.

Detailed description

To investigate ED50, Dixon's up and down method will be used.

Conditions

• Agitation

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	dexmedetomidine, 0.1ug/kg up or down

Timeline

• Start date: 2011-06-01
• Primary completion: 2011-12-01
• Completion: 2012-02-01
• First posted: 2011-06-16
• Last updated: 2011-06-16

Locations

1 site across 1 country: South Korea