Clinical Trials Directory

Trials / Completed

CompletedNCT01358370

A Retrospective Natural History Study of Patients With Lysosomal Acid Lipase Deficiency/Wolman Phenotype

Status
Completed
Phase
Study type
Observational
Enrollment
40 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This is a Natural History study to characterize key aspects of the clinical course of lysosomal acid lipase (LAL) deficiency/Wolman phenotype in patients.

Detailed description

The objective of this study is to characterize key aspects of the clinical course of LAL deficiency/Wolman phenotype in patients including, but not limited to, survival and growth parameters, to serve as a historical control to inform the evaluation and care of affected patients and to provide a reference for efficacy studies of enzyme replacement or other novel therapies.

Conditions

Timeline

Start date
2010-11-01
Primary completion
2013-01-01
Completion
2013-03-01
First posted
2011-05-23
Last updated
2016-06-27

Locations

14 sites across 5 countries: United States, Canada, France, Italy, United Kingdom

Source: ClinicalTrials.gov record NCT01358370. Inclusion in this directory is not an endorsement.